We are seeking an ambitious, recently graduated and committed post-doctoral fellow to work on the role of protein tyrosine phosphatases in the immune system. The project aims notably at completing existing research program in immunotherapy and opening novel means by which to control immune cells through small inhibitors and biological modulators of protein tyrosine phosphatases. Moreover, it involves the characterization of T-cell exhaustion mechanism and the role of PTP in system biology of aging immune system. Using various drug-like compounds and a series of genetic and genome editing tools, in both human systems and animal models, we are advancing several innovative approaches to improve current anti-cancer immunotherapies.
The laboratory of Prof. Michel L. Tremblay has been interacting with clinician scientists at McGill University and colleagues of various research institutes in Montreal and internationally. A component of this work is to interact with private sector biotechnology and pharmaceutical companies aiming at novel discoveries and application of cancer immunotherapy. Located in the dynamic environment of the Rosalind and Morris Goodman Cancer Research Centre (GCRC) in downtown Montreal, the GCRC has access to a large number of core facilities, including a modern FACS facility that allow rapid and professional analysis of immune cells and their signaling regulations.
Prospective candidate is expected to apply for competitive internal and external funding. Internal funding information: http://www.mcgillgcrc.com/index.php?option=com_content&view=article&id=22&Itemid=176
Recent Doctoral degree in Immunology or in a related biomedical sciences field.
Background in cancer research and immune systems, teamwork proficient and multitasking. Knowledge of several molecular and cellular techniques such as Flow Cytometry, FlowJo, qtPCR, cell culture and differentiation, cytokine biology and others. Excellent writing and speaking skills, knowledge of mouse models and humanized mouse approaches, microscopy and associated software for imaging, bioinformatics, graphic design statistics, and datamining.
OTHER QUALIFYING SKILLS & ABILITIES
1. English and French proficiency necessary to conduct cognitive assessments in both languages.
2. Excellent organizational abilities to manage complex, multi‐faceted projects.
3. Excellent interpersonal skills (direct experience with research participants preferred).
Interested individuals should send their CV and a cover letter describing their interest directly to Professor M. L. Tremblay by email at: email@example.com.
Three reference letters will be requested.