The projects to be undertaken are supported by the Canadian Institutes of Health Research (CIHR) and the Canadian Cancer Society, and will explore the roles of mouse and human innate-like T lymphocytes in host responses to viral pathogens (e.g., influenza A viruses and SARS-CoV-2) and sepsis-causing microbes, and in regulation of antitumor immune surveillance.
The ideal candidate has a PhD, MD, DVM (or equivalent), and is well versed in immunological techniques, including flow cytometry. Additional background in RNA sequencing analyses and experience in mouse models of malignant and infectious diseases are preferred. The candidate should be able to work both independently and as an effective member of a collaborative and growing team.
Research stipend will be competitive and commensurate with experience and sought expertise. Review of applications will begin immediately and continue until the position is filled. Only shortlisted candidates will be contacted.
Applicants should submit (preferably by e-mail) their curriculum vitae, a brief statement of research interests, and names and contact information of three references to:
Dr. Mansour Haeryfar
Departments of Microbiology & Immunology, Medicine, and Surgery
1151 Richmond Street, London, ON, N6A 5C1 CANADA
The overarching goal of our research is to further our understanding of conventional and innate-like invariant T cell responses in health and disease. We are particularly interested in cytotoxic T lymphocytes (CTLs), invariant natural killer T (iNKT) cells and mucosa-associated invariant T (MAIT) cells and their therapeutic potentials in various conditions, primarily in cancer and infectious disease. We use preclinical models in our mechanistic studies as well as clinical samples in an effort to translate our findings “from the benchtop to the bedside”. The knowledge to be gained is expected to lead to novel disease-tailored immunotherapies.