The Pioli lab is looking for a MSc graduate student to join the lab in September 2024 or earlier.
Our lab focuses on understanding the development and function of antibody-secreting cells (ASCs). ASCs are terminally differentiated B cells which produce protective antibodies under normal conditions. However, in certain circumstances, ASCs secrete autoreactive antibodies which promote autoimmune disease pathogenesis. In certain diseases such as myasthenia gravis, pathogenic ASCs are thought to originate in the thymus; however, the mechanisms leading to the generation of these cells are not fully understood.
The putative MSc student will focus on understanding how ASCs are generated in the thymus under both normal and autoimmune-promoting conditions. Results from these studies will provide a greater understanding of the etiology of autoimmune diseases that are driven by thymus ASCs.
A cumulative weighted average of at least a 80% (USask grade system equivalent) in the last two years of study (i.e. 60 credit units). A four-year honours degree, or equivalent, from a recognized college or university in an academic discipline relevant to the proposed field of study.
The Pioli lab is equal opportunity and welcomes applications from all individuals. However, applicants that are Canadian citizens or permanent residents will be given priority.
Dr. Pete Pioli